Mucopolysaccharides and sodium metabolism.

Mucopolysaccharides and Sodium Metabolism

This paper deals with the possible relationship between a native, negatively charged polyelectrolyte, chondroitin sulfate, and sodium metabolism. The physical chemical property of decreased activity of the cations Na, K and Ca in chondroitin sulfate is described. The data of experiments indicating an alteration in the inueoprotein metabolism of the cartilage of the rabbit's ear in response to t...

Myocardial connective tissue metabolism in response to injury. II. Investigation of the mucopolysaccharides involved in isoproterenol-induced necrosis and repair in rat hearts.

Myocardial necrosis was produced in rats by administering isoproterenol, and the increase in hexosamine-containing materials in the injured myocardium was investigated. Total hexosamine, galactosamine, neutral sugars, and uronic acids were determined on various fractions isolated from the hearts. Mucopolysaccharides were precipitated as the cetyl pyridinium chloride complex and fractionated acc...

The Metabolism of Mucopolysaccharides in Animals

The turnover of the acid mucopolysaccharides, hyaluronic acid (HA) and chondroitinsulfuric acid (CSA), of skin has been studied in normal rats (1) and in animals treated with the adrenocortical hormones, 17-hydroxycorticosterone and 11-dehydro-17-hydroxycorticosterone (2). It was shown that the administration of these adrenal steroids to otherwise normal rats resulted in a decreased turnover of...

The estimation of heparin and similar substances in human blood and tissues using a combined biological and colorimetric method with paper electrophoretic studies.

Heparin and other acid mucopolysaccharides were extracted from various tissues by a modification of the method previously described (Bassiouni, 1953). The dye mucopolysaccharides complex obtained was resolved into its components with formamide: the acid mucopolysaccharides were precipitated with methyl alcohol in the presence of electrolyte (sodium chloride). A solution of the purified polysacc...

Metabolism of the mucopolysaccharides of connective tissue.